peony and licorice side effects

van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. 2000;20(1):38-41. Rev Med Brux 2008;29(5):490-493. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Antiviral Res 1987;7(2):99-107. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. Comparative Study of the Effect of Licorice Muco-adhesive Film on Radiotherapy Induced Oral Mucositis, A Randomized Controlled Clinical Trial. Plant Description. Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. 17. Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo. View abstract. Note: Results may vary from person to person, depending on the skin type. ""- . A double-blind, randomized, placebo-controlled, multicenter trial. Ann Mtg Digestive Disease Week 1999 May. View abstract. Iran J Pharm Res. Amato P, Christophe S, Mellon PL. Lancet 2-10-1979;1(8111):319. View abstract. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707. Turpie AG, Runcie J, Thomson TJ. View abstract. Kinoshita T, Maruyama K, Yamamoto N, Saito I. Zhonghua Yi Xue Za Zhi 1983;63:477-81. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. Taking peony along with medications that also slow blood clotting might increase the risk of bruising and bleeding. View abstract. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. 2008;9(3):88-98. View abstract. Eur.Arch.Paediatr.Dent 2010;11(6):274-278. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. [Effectiveness of interferon, glycyrrhizin combination therapy in patients with chronic hepatitis C]. Sakamoto S, Kudo H, Suzuki S, et al. Some birth control pills contain estrogen. Pharmazie 2010;65(8):624-8. 2003;23(8):593-595. View abstract. Neth J Med 2005;63:149-50. 2011;25(2):312-313. J Pharm Pharmacol 2003;55:1275-82. But the potential side effects are real enough. View abstract. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. The efficacy of an ayurvedic preparation of yashtimadhu (Glycyrrhiza glabra) on radiation-induced mucositis in head-and-neck cancer patients: A pilot study. J Nat Prod 1980;43(2):259-269. Mohire, N. C. and Yadav, A. V. Chitosan-based polyherbal toothpaste: as novel oral hygiene product. View abstract. [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. Overview. He X, Xing D, Ding Y, et al. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Lin SH, Yang SS, Chau T, Halperin ML. How Much Is Too Much? Ultrastruct Pathol 1992;16(5):529-535. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Pulmonary edema following a licorice binge. Licorice might decrease how well cisplatin works. Cisplatin is used to treat cancer. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Izv Akad Nauk Ser Biol 1997;2:235-7. . View abstract. N Engl J Med. Wen Y, Tang Y, Li M, Lai Y. Medicinal herbs: modulation of estrogen action. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Madisch A, Melderis H, Mayr G, et al. Lee, C. K., Park, K. K., Lim, S. S., Park, J. H., and Chung, W. Y. This Halloween, you'll want to stay vigilant about the candy . Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. BMJ Case Rep 2012;2012. Mumoli, N. and Cei, M. Licorice-induced hypokalemia. Fan ZJ, Liu JM, Li XX, et al. An open study of 100 women with uterine fibroids showed that peony reduced the size of . View abstract. View abstract. Crit Care 2011;15(1):R64. View abstract. Biol Pharm Bull. View abstract. Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. J Ethnopharmacol 2002;81:101-4.. View abstract. 2020;383(13):1263-1275. Nutrition 2002;18(3):268-273. What are the side-effects of taking liquorice? Some believe it may also increase estrogen and prolactin levels in women, though more research is warranted. 1991;78(1-2):1-6. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. Life Sci 1993;53(5):PL63-8. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. View abstract. To learn more about how herbs are used to treat infertility, see this article. J Assoc Physicians India 1989;37(10):647. Ohta H, Ni JW, Matsumoto K, et al. The U.S. Food and Drug . View abstract. 1987;(10):46-48. Mol Cell Endocrinol. Middle East J Anaesthesiol. Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. View abstract. View abstract. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. View abstract. View abstract. This formula has also been shown to dramatically relieve various types of spasmodic pain such as muscle cramps in the back and legs (restless legs) stiff muscles premenstrual cramping sciatica and abdominal pain. Lee, S., Lim, J. M., Jin, M. H., Park, H. K., Lee, E. J., Kang, S., Kim, Y. S., and Cho, W. G. Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin. View abstract. Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract. BMJ Case Rep. 2012 Oct 19;2012. Chang GH, Lin YS, Hsu KH, et al. Caubet-Kamar, N., Tubery, M., Garrouste, C., Lauque, D., and Kamar, N. Harmful effect of saline infusion in a patient with glycyrrhizic acid poisoning. Clin Neurol Neurosurg 1993;95(1):35-37. View abstract. Zhongguo Zhong.Yao Za Zhi 2009;34(21):2695-2700. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. View abstract. View abstract. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. Gibertoni, M., Bonito, V., Colombo, A., Falasca, A., and Nichelli, P. [Licorice-induced myopathy. View abstract. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. View abstract. 2013 Jun;22(2):173-8. 2017;109:182-190. 17. View abstract. The dose of your warfarin might need to be changed. Monograph. 1. Steroids 2005;70(8):538-542. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. . Not too many side effects of peony tea that we need to worry about. Mechanism of anti-inflammatory action of glycyrrhizin: effect on neutrophil functions including reactive oxygen species generation. View abstract. Zhang YD, Lorenzo B, Reidenberg MM. Ned.Tijdschr Geneeskd. Microbiol Immunol 2000;44(9):799-804. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. The Potential Benefits and Side Effects of the White Peony Root. Kwon S, Jin C, Cho SY, et al. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. View abstract. 1979;14(5):605-607. View abstract. White peony ( bai shao in Chinese) is root without any bark, while red peony . Yamaguchi, H., Kidachi, Y., Kamiie, K., Noshita, T., Umetsu, H., and Ryoyama, K. Glycyrrhetinic acid induces anoikis-like death and cytoskeletal disruption in the central nervous system tumorigenic cells. 2012;18(4):534-543. J Tradit.Chin Med 2010;30(1):47-50. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. View abstract. View abstract. N Engl J Med 1990;322:850. View abstract. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. View abstract. Glycyrrhizin-Induced Pseudohyperaldosteronism: A Case Report. Liquorice and hypertension. View abstract. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. An Med Interna 1995;12(1):33-35. View abstract. Peony might change how quickly the liver breaks down these medications. Taking licorice and loop diuretics together might make potassium levels drop too low. Man SC, Li XB, Wang HH, et al. Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! View abstract. Fatal hypokalaemic alkalosis with tetany during liquorice and P.A.S. Int J Nurs Stud 2016;63:9-17. View abstract. Zhong Yao Cai 2000;23:557-60. . Licorice might increase how quickly the body breaks down paclitaxel. View abstract. Bell ZW, Canale RE, Bloomer RJ. View abstract. J Altern Complement Med. 1994;14:207-9, 195. . J Clin Hypertens (Greenwich) 2008;10:153-7. Chem Pharm Bull (Tokyo) 1994;42(5):1056-1062. Licorice can be used orally with Peony to treat women with Polycystic Ovary Syndrom to increase fertility; it can also treat patients with abnormal Prolactin, muscle spasms, or to reduce the pain of cancer. Fitoterapia 2004;75:45-9.. View abstract. Treatment of functional dyspepsia with a herbal preparation. Epilepsy Res 2021;176:106735. Gatica-Ortega ME, Pastor-Nieto MA. Hasani-Ranjbar, S., Nayebi, N., Moradi, L., Mehri, A., Larijani, B., and Abdollahi, M. The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. The effects of licorice containing diphenhydramine solution on recurrent aphthous stomatitis: A double-blind, randomized clinical trial. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Ital J Neurol Sci 1983;4(4):493-497. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. J Clin Endocrinol Metab 1990;70(6):1637-1643. Armanini, D., Mattarello, M. J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., and Palermo, M. Licorice reduces serum testosterone in healthy women. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. May Harm Baby During Pregnancy. "Water pills" can also decrease potassium levels. Planta Med 2003;69(12):1113-1118. J Clin Psychopharmacol 1997;17(3):234-235. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. View abstract. View abstract. WebMD does not provide medical advice, diagnosis or treatment. View abstract. J Biol Response Mod 1985;4:551-84. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. Zhang W, Dai SM. Large amounts of licorice can decrease potassium levels in the body. Xu, L., Jiang, J., and Du, F. Z. View abstract. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. 2020;50:102401. View abstract. Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Eur Neurol 1992;32(1):44-51. This could change the effects and side effects of these medications. J Ethnopharmacol 2004;94:339-44. . Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. J Contemp.Dent Pract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Am J Chin Med 1996;24:165-8. View abstract. Read more. View abstract. OTHER NAME(S): Acide Glycyrrhizique, Acide Glycyrrhizinique, Alca. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. Yang HO, Ko WK, Kim JY, Ro HS. J Clin Pharm Ther 2001;26:271-8. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. A laboratory evaluation of the antibacterial and cytotoxic effect of Liquorice when used as root canal medicament. View abstract. Murck H, Lehr L, Hahn J, Braunisch MC, Jezova D, Zavorotnyy M. Adjunct Therapy With Glycyrrhiza Glabra Rapidly Improves Outcome in Depression-A Pilot Study to Support 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Inhibition as a New Target. Licorice can decrease how quickly the body breaks down corticosteroids. I like herbal and fuit teas and a particular favourite of mine contains liquorice. The efficacy and safety of the combination of total glucosides of peony and leflunomide for the treatment of rheumatoid arthritis: a systematic review and meta-analysis. View abstract. View abstract. BJU Int 2000;85:481-5. Hypertension encephalopathy after liquorice ingestion. Arch Pharm Res 2003;26(10):832-839. Dobbins, K. R. and Saul, R. F. Transient visual loss after licorice ingestion. B. Licorice-associated reversible cerebral vasoconstriction with PRES. 2000;20(3):173-175. Jafari Z, Emtiazy M, Sohrabvand F, et al. J Pharmacol Exp Ther 2006;316:1369-77. In a 30-day study in 50 adults with indigestion, taking a 75-mg licorice . Gut 1978;19(9):779-782. Indian J Med Res 1993;98:69-74. Licorice consumption and serum testosterone in healthy man. View abstract. View abstract. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. White Peony Tea Side Effects. View abstract. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. . 10. View abstract. Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., and Aviram, M. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. View abstract. View abstract. Phytomedicine 2003;10:271-85. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. Life Sci 9-27-2002;71(19):2267-2277. 2010;33(2):321-324. Pharm Biol 2021;59(1):1276-1285. PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy View abstract. Doeker, B. M. and Andler, W. Liquorice, growth retardation and Addison's disease. View abstract. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. View abstract. Some sources claim that it's contraindicated during pregnancy . Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. It may disrupt the production of sex hormones ( 9 ). Pfeifer BL, Pirani JF, Hamann SR, Klippel KF. View abstract. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. View abstract. Kitagawa, I., Chen, W. Z., Hori, K., Harada, E., Yasuda, N., Yoshikawa, M., and Ren, J. Postgrad Med J 2003;79:115-6.. View abstract. Severe hypokalaemia with paralysis induced by small doses of liquorice. Asian Medical Journal 1984;26(7):423-438. Pathogenetic considerations and presentation of a clinical case]. View abstract. 2009;14(1):64-65. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Pseudohyperaldosteronism, liquorice, and hypertension. The chemicals in licorice are thought to . Ann Pharmacother 2003;37(6):836-838. Neth J Med 2005;63:119-20. Kang, J. H., Park, Y. H., Choi, S. W., Yang, E. K., and Lee, W. J. Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells. Cancer 1997;79(8):1494-1500. The author has an hindex of 4, co-authored 18 publication(s) receiving 46 citation(s). Psychoneuroendocrinology. View abstract. In general, the safety and effectiveness of alternative medicines have not been scientifically proven and remain largely unknown. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. View abstract. View abstract. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. Sheehan M, Rustin MHA, Atherton DJ, et al. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. But, she survived . 2020. Chen LC, Chou MH, Lin MF, Yang LL. View abstract. J Peripher.Nerv.Syst. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. Exp Ther Med 2016;11(3):1135-41. Nephrologie 1993;14(4):177-181. Murakami, T. and Uchikawa, T. Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. Some of these health benefits have also . Peony might block chemicals that can cause pain and swelling . Li G, Simmler C, Chen L, et al. West J Med 1997;167(3):184-185. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. View abstract. 2019;35:329-41. Contact Dermatitis Due to Paeonia (Peony). Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. Med Princ Pract 2010;19(6):485-489. Exp.Mol.Med 12-31-2003;35(6):467-474. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? J Clin Psychopharmacol 2016;36(6):572-9. Kumada T, et al. Maeda T, Shinozuka K, Baba K, et al. Mu Y, Zhang J, Zhang S, et al. Zhong.Xi.Yi.Jie.He.Za Zhi. Vestn.Dermatol.Venerol. Exp Med Surg 1969;27:411-20. van Marle J, Aarsen PN, Lind A, van Weeren-Kramer J. Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium. J Clin Psychopharmacol 2008;28(3):264-370. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. Lower potassium levels can cause those abnormal heart arrhythmias. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. Licorice, tobacco chewing, and hypertension. Tewari SN, Wilson AK. View abstract. View abstract. View abstract. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. Some medications are moved in and out of cells by pumps. View abstract. Eur J Drug Metab Pharmacokinet. View abstract. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. They also have a range of other intriguing activities. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. van der Zwan A. This can increase the effects and side effects of corticosteroids. View abstract. View abstract. . Therapeutic Research Faculty 2020. View abstract. The effects of dietary licorice flavonoid oil supplementation on body balance control in healthy middle-aged and older Japanese women undergoing a physical exercise intervention: a randomized, double-blind, placebo-controlled trial. View abstract. Blood Press 2009;18:192-5. J Ethnopharmacol. Evaluation of contextual and demographic factors on licorice effects on reducing hot flashes in postmenopause women.